![]() ![]() Evidence of this is observed in patients who are deficient in hemodialysis. MGP inhibits calcium from hardening and building up on arterial walls, but without Vitamin K2, the modification process will not activate MGP. ![]() The way Vitamin K2 prevents calcification is by interacting with other proteins to modify a protein called Matrix Gla protein (MGP). These plaques can cause blockages and eventually lead to heart attacks or strokes. Calcium accumulation can also cause the build up and formation of plaques. This is detrimental because the elasticity of arteries plays an essential role in many physiological processes. Calcification of the vascular wall can cause arteries to harden. As calcium begins to accumulate along vascular walls, it can cause two problems. Interestingly, calcium has the ability to embed itself into the walls of blood vessels, and this can prove to be problematic if it occurs in excess. Calcium is an integral part of vascular health. ![]()
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